All natural, no preservatives, made in the USA. A complete food source for orphaned or rejected puppies or those nursing, but needing supplemental feeding. Also recommended for growing puppies or adult dogs that are stressed and require a source of highly digestible nutrients. Esbilac is a complete diet for puppies fortified with vitamins and minerals. Esbilac s life saving formula closely matches bitch s milk in protein and energy and has set the standard in canine neonatal nutrition for over 70 years. Powder formula is easy to mix with water.